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Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?
- a)Trichoderma polysporum
- b)Mucor pucillus
- c)Monascus purpureus
- d)Streptococcus pyogenes
Correct answer is option 'A'. Can you explain this answer?
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Cyclosporin A is used as an immunosuppressive agent in organ-transpla...
Microbe Producing Cyclosporin A: Trichoderma polysporum
Cyclosporin A is a potent immunosuppressive drug that is widely used in organ transplant patients to prevent organ rejection. It is produced by the filamentous fungus Trichoderma polysporum. Let's understand why Trichoderma polysporum is the correct answer.
Trichoderma polysporum:
- Trichoderma polysporum is a species of filamentous fungus belonging to the genus Trichoderma.
- It is commonly found in soil and decaying organic matter.
- It is known for its ability to produce various secondary metabolites, including cyclosporin A.
Production of Cyclosporin A:
- Cyclosporin A is a cyclic undecapeptide with immunosuppressive properties.
- Trichoderma polysporum produces cyclosporin A through a complex biosynthetic pathway involving multiple enzymatic reactions.
- The genes responsible for the synthesis of cyclosporin A are located on a specific region of the fungal genome called the cyclosporin A gene cluster.
- The expression of these genes is regulated by various factors such as nutrient availability, pH, and temperature.
Importance of Cyclosporin A:
- Cyclosporin A is primarily used as an immunosuppressive agent in organ transplant patients.
- It works by inhibiting the activity of T-cells, which are responsible for initiating immune responses.
- By suppressing the immune system, cyclosporin A helps prevent rejection of transplanted organs.
- It is also used in the treatment of various autoimmune diseases such as rheumatoid arthritis and psoriasis.
Conclusion:
In conclusion, Trichoderma polysporum is the microbe that produces cyclosporin A. This filamentous fungus has the ability to synthesize cyclosporin A through a complex biosynthetic pathway. The discovery of this immunosuppressive compound has revolutionized organ transplantation and has been instrumental in improving the success rate of organ transplant procedures.
Cyclosporin A is a potent immunosuppressive drug that is widely used in organ transplant patients to prevent organ rejection. It is produced by the filamentous fungus Trichoderma polysporum. Let's understand why Trichoderma polysporum is the correct answer.
Trichoderma polysporum:
- Trichoderma polysporum is a species of filamentous fungus belonging to the genus Trichoderma.
- It is commonly found in soil and decaying organic matter.
- It is known for its ability to produce various secondary metabolites, including cyclosporin A.
Production of Cyclosporin A:
- Cyclosporin A is a cyclic undecapeptide with immunosuppressive properties.
- Trichoderma polysporum produces cyclosporin A through a complex biosynthetic pathway involving multiple enzymatic reactions.
- The genes responsible for the synthesis of cyclosporin A are located on a specific region of the fungal genome called the cyclosporin A gene cluster.
- The expression of these genes is regulated by various factors such as nutrient availability, pH, and temperature.
Importance of Cyclosporin A:
- Cyclosporin A is primarily used as an immunosuppressive agent in organ transplant patients.
- It works by inhibiting the activity of T-cells, which are responsible for initiating immune responses.
- By suppressing the immune system, cyclosporin A helps prevent rejection of transplanted organs.
- It is also used in the treatment of various autoimmune diseases such as rheumatoid arthritis and psoriasis.
Conclusion:
In conclusion, Trichoderma polysporum is the microbe that produces cyclosporin A. This filamentous fungus has the ability to synthesize cyclosporin A through a complex biosynthetic pathway. The discovery of this immunosuppressive compound has revolutionized organ transplantation and has been instrumental in improving the success rate of organ transplant procedures.
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Cyclosporin A is used as an immunosuppressive agent in organ-transpla...
Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Cyclosporine belongs to a class of drugs known as immunosuppressants. Cyclosporin A is produced by the fungus Trichoderma polysporum.
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Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer?
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Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer?.
Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Cyclosporin A is used as an immunosuppressive agent in organ-transplant patients. Which of the following microbes produces cyclosporine A?a)Trichoderma polysporumb)Mucor pucillusc)Monascus purpureusd)Streptococcus pyogenesCorrect answer is option 'A'. Can you explain this answer?.
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