Which of the following is the correct sequence/route of the secretory ...
The correct sequence for the pathway of a secretory product typically follows these steps:
Synthesis in the Rough Endoplasmic Reticulum (RER) - Proteins are synthesized and undergo initial modifications.
Transport via Vesicles - Proteins are packed into vesicles that bud off from the RER.
Cis Face of the Golgi Apparatus (GB) - Vesicles fuse with the cis face of the Golgi body, where further modification of proteins occurs.
Transit Through Golgi Apparatus - Proteins move from the cis to the trans region of the Golgi, undergoing further modifications.
Vesicles to Plasma Membrane - Finished proteins are packaged into vesicles that bud off from the trans face of the Golgi and are transported to the plasma membrane.
Therefore, Option A accurately describes the typical secretory pathway, starting from the Endoplasmic Reticulum (ER), moving through the Golgi body from the cis to the trans region, and finally to the plasma membrane.
This question is part of UPSC exam. View all NEET courses
Which of the following is the correct sequence/route of the secretory ...
Correct Sequence of Secretory Product: Option A
The correct sequence for the route of secretory products in a eukaryotic cell is option A:
ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membrane
This pathway is essential for the synthesis and secretion of proteins and other molecules.
Detailed Explanation
1. Endoplasmic Reticulum (ER)
- The process begins in the Rough Endoplasmic Reticulum (RER), where proteins are synthesized. Ribosomes on the RER produce proteins that are destined for secretion.
2. Vesicles
- Once synthesized, these proteins are packaged into transport vesicles that bud off from the ER.
3. Golgi Apparatus (GB)
- The vesicles then travel to the Golgi Apparatus. They fuse with the cis region of the Golgi, where they undergo further modification, sorting, and packaging.
4. Trans Region of GB
- After modifications, proteins move through the Golgi and reach the trans region, where they are prepared for secretion.
5. Vesicle to Plasma Membrane
- The proteins are then packaged into new vesicles that bud off from the trans region of the Golgi apparatus. These vesicles travel to the plasma membrane.
6. Exocytosis
- Finally, the vesicles fuse with the plasma membrane, releasing their contents outside the cell through the process of exocytosis.
Conclusion
This sequence is crucial for the proper functioning of cellular processes, ensuring that proteins reach their intended destinations efficiently.