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Which of the following is the correct sequence/route of the secretory product?
- a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membrane
- b)RER → GB → Lysosome → Nuclear membrane → Plasma membrane
- c)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membrane
- d)Lysosome → ER → GB → Vesicles → Cell membrane
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which of the following is the correct sequence/route of the secretory ...
The correct sequence for the pathway of a secretory product typically follows these steps:
Synthesis in the Rough Endoplasmic Reticulum (RER) - Proteins are synthesized and undergo initial modifications.
Transport via Vesicles - Proteins are packed into vesicles that bud off from the RER.
Cis Face of the Golgi Apparatus (GB) - Vesicles fuse with the cis face of the Golgi body, where further modification of proteins occurs.
Transit Through Golgi Apparatus - Proteins move from the cis to the trans region of the Golgi, undergoing further modifications.
Vesicles to Plasma Membrane - Finished proteins are packaged into vesicles that bud off from the trans face of the Golgi and are transported to the plasma membrane.
Therefore, Option A accurately describes the typical secretory pathway, starting from the Endoplasmic Reticulum (ER), moving through the Golgi body from the cis to the trans region, and finally to the plasma membrane.
Synthesis in the Rough Endoplasmic Reticulum (RER) - Proteins are synthesized and undergo initial modifications.
Transport via Vesicles - Proteins are packed into vesicles that bud off from the RER.
Cis Face of the Golgi Apparatus (GB) - Vesicles fuse with the cis face of the Golgi body, where further modification of proteins occurs.
Transit Through Golgi Apparatus - Proteins move from the cis to the trans region of the Golgi, undergoing further modifications.
Vesicles to Plasma Membrane - Finished proteins are packaged into vesicles that bud off from the trans face of the Golgi and are transported to the plasma membrane.
Therefore, Option A accurately describes the typical secretory pathway, starting from the Endoplasmic Reticulum (ER), moving through the Golgi body from the cis to the trans region, and finally to the plasma membrane.
Topic in NCERT: Golgi apparatus
Line in NCERT: "Materials to be packaged in the form of vesicles from the ER fuse with the cis face of the golgi apparatus and move towards the maturing face."
Most Upvoted Answer
Which of the following is the correct sequence/route of the secretory ...
Correct Sequence of Secretory Product Pathway
The correct sequence of the secretory pathway is outlined in option 'A':
ER → Vesicles → Cis region of Golgi Body → Trans region of Golgi Body → Vesicle → Plasma membrane
Explanation of the Pathway
1. Endoplasmic Reticulum (ER)
- The secretory proteins are synthesized in the Rough Endoplasmic Reticulum (RER), where ribosomes are attached.
- The RER plays a crucial role in the initial post-translational modifications and folding of proteins.
2. Vesicles
- Once proteins are synthesized and properly folded, they are packaged into transport vesicles.
- These vesicles bud off from the ER and are directed toward the Golgi apparatus.
3. Golgi Apparatus: Cis Region
- The vesicles fuse with the Cis region of the Golgi body, where they undergo further modifications.
- Here, proteins may undergo glycosylation and other enzymatic processes.
4. Golgi Apparatus: Trans Region
- Proteins are then moved through the Golgi apparatus to the Trans region, where they are sorted and packaged for delivery to their final destinations.
5. Final Vesicle Formation
- After processing, proteins are enclosed in new vesicles that bud off from the Trans region of the Golgi.
6. Plasma Membrane
- These vesicles are transported to the plasma membrane, where they fuse with it to release their contents outside the cell or integrate with the membrane.
Conclusion
- The pathway outlined in option 'A' accurately represents the route taken by secretory products from synthesis to secretion, emphasizing the critical roles of the ER and Golgi apparatus in this process.
The correct sequence of the secretory pathway is outlined in option 'A':
ER → Vesicles → Cis region of Golgi Body → Trans region of Golgi Body → Vesicle → Plasma membrane
Explanation of the Pathway
1. Endoplasmic Reticulum (ER)
- The secretory proteins are synthesized in the Rough Endoplasmic Reticulum (RER), where ribosomes are attached.
- The RER plays a crucial role in the initial post-translational modifications and folding of proteins.
2. Vesicles
- Once proteins are synthesized and properly folded, they are packaged into transport vesicles.
- These vesicles bud off from the ER and are directed toward the Golgi apparatus.
3. Golgi Apparatus: Cis Region
- The vesicles fuse with the Cis region of the Golgi body, where they undergo further modifications.
- Here, proteins may undergo glycosylation and other enzymatic processes.
4. Golgi Apparatus: Trans Region
- Proteins are then moved through the Golgi apparatus to the Trans region, where they are sorted and packaged for delivery to their final destinations.
5. Final Vesicle Formation
- After processing, proteins are enclosed in new vesicles that bud off from the Trans region of the Golgi.
6. Plasma Membrane
- These vesicles are transported to the plasma membrane, where they fuse with it to release their contents outside the cell or integrate with the membrane.
Conclusion
- The pathway outlined in option 'A' accurately represents the route taken by secretory products from synthesis to secretion, emphasizing the critical roles of the ER and Golgi apparatus in this process.
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Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer?
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Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer? for NEET 2025 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer?.
Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer? for NEET 2025 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer? covers all topics & solutions for NEET 2025 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Which of the following is the correct sequence/route of the secretory product?a)ER → Vesicles → Cis region of GB → Trans region of GB → Vesicle → Plasma membraneb)RER → GB → Lysosome → Nuclear membrane → Plasma membranec)ER → Vesicles → Trans region of GB → Cis region of GB → Vesicles → Plasma membraned)Lysosome → ER → GB → Vesicles → Cell membraneCorrect answer is option 'A'. Can you explain this answer?.
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