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In human, aniridia (a type of blindness resulting from absence of an iris) is due to a different dominant gene. Migraine (a sickening headache) is due to a different dominant gene. A man with aniridia, whose mother was not blind, marries a woman who suffers from migraine. The woman's father did not suffer from migraine. In what proportion of their children would both aniridia and migraine be expected to occur?
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In human, aniridia (a type of blindness resulting from absence of an i...
Genetic Background
- Aniridia is a condition caused by a dominant gene (let's denote it as A). Affected individuals have at least one A allele. The man's mother was not blind, indicating she must be homozygous recessive (aa) for this trait.
- Therefore, the man must have inherited one A allele from his father (who is an affected individual) and one a allele from his mother (aa). His genotype is Aa.
- Migraine is also caused by a different dominant gene (let's denote it as M). The woman's father does not suffer from migraine, which means he is homozygous recessive (mm). Since she suffers from migraine, she must have at least one M allele. Therefore, her genotype is Mm.
Parental Genotypes
- Man (Aniridia): Aa
- Woman (Migraine): Mm
Possible Gametes
- The man can produce gametes: A, a
- The woman can produce gametes: M, m
Offspring Combinations
- The possible offspring genotypes from these gametes are:
- AM (Aniridia & Migraine)
- Am (Aniridia & No Migraine)
- aM (No Aniridia & Migraine)
- am (No Aniridia & No Migraine)
Expected Proportions
- Out of the four possible combinations:
- 1 (AM) will have both aniridia and migraine.
- 1 (Am) will have aniridia only.
- 1 (aM) will have migraine only.
- 1 (am) will have neither condition.
Conclusion
- The proportion of their children expected to have both aniridia and migraine is 1 out of 4, or 25%.
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In human, aniridia (a type of blindness resulting from absence of an iris) is due to a different dominant gene. Migraine (a sickening headache) is due to a different dominant gene. A man with aniridia, whose mother was not blind, marries a woman who suffers from migraine. The woman's father did not suffer from migraine. In what proportion of their children would both aniridia and migraine be expected to occur?
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In human, aniridia (a type of blindness resulting from absence of an iris) is due to a different dominant gene. Migraine (a sickening headache) is due to a different dominant gene. A man with aniridia, whose mother was not blind, marries a woman who suffers from migraine. The woman's father did not suffer from migraine. In what proportion of their children would both aniridia and migraine be expected to occur? for UPSC 2024 is part of UPSC preparation. The Question and answers have been prepared according to the UPSC exam syllabus. Information about In human, aniridia (a type of blindness resulting from absence of an iris) is due to a different dominant gene. Migraine (a sickening headache) is due to a different dominant gene. A man with aniridia, whose mother was not blind, marries a woman who suffers from migraine. The woman's father did not suffer from migraine. In what proportion of their children would both aniridia and migraine be expected to occur? covers all topics & solutions for UPSC 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for In human, aniridia (a type of blindness resulting from absence of an iris) is due to a different dominant gene. Migraine (a sickening headache) is due to a different dominant gene. A man with aniridia, whose mother was not blind, marries a woman who suffers from migraine. The woman's father did not suffer from migraine. In what proportion of their children would both aniridia and migraine be expected to occur?.
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