Which cell organelle secretes zymogen granules :-a)Lysosomesb)Smooth E. R.c)Golgibodyd)SphaerosomesCorrect answer is option 'B'. Can you explain this answer?

Question

Answer

The Golgi apparatus is a system of membranous cisternae and vesicles arranged in stacks near the nucleus. Secretory vesicles or granules usually contain specific substances synthesized by cells that are exported to the extracellular medium. They include zymogen granules, mucous droplets, and mast cell granules.

Answer

A
zymogen or proenzyme
is an inactive enzyme precursor. A
zymogen
requires a biochemical change such as a hydrolysis reaction revealing the active site, or changing the configuration to reveal the active site for it to become an active enzyme. Smooth endoplasmic reticulum secretes
zymogen
. The smooth endoplasmic reticulum has functions in several metabolic processes. It synthesizes lipids, phospholipids, and steroids. The general structure of the endoplasmic reticulum is a network of membranes called cisternae. These sac-like structures are held together by the cytoskeleton. The network of smooth endoplasmic reticulum allows for an increased surface area to be devoted to the action or storage of key enzymes and the products of these enzymes.

Answer

Correct answer B
Most zymogen granules begin formation where the zymogen are first formed the endoplamic reticulum.The ER is like the cells factory its where the protein are made from. They are sent to the golgi. The golgi like the cells post office where finished product are packed and shipped to dufferent part of the cellfrom the golgi fully formed zymogen granules behin to gather at the apex or the top the vell.

Answer

I think option c is correct & not b

Answer

Correct answer is smooth reticulum

Answer

Secretion of Zymogen Granules by Smooth Endoplasmic Reticulum (ER)

The correct answer is option 'B' - Smooth Endoplasmic Reticulum (ER). The smooth ER is responsible for the synthesis and secretion of zymogen granules in cells.

Explanation:
The smooth endoplasmic reticulum (ER) is a network of tubules and vesicles that lack ribosomes on its surface. It plays a crucial role in various cellular functions, including the synthesis of lipids, metabolism of carbohydrates, detoxification of drugs and toxins, and storage and release of calcium ions.

Function of Smooth ER in Zymogen Granule Secretion:
Zymogen granules are membrane-bound vesicles found in various secretory cells, particularly in the exocrine pancreas. These granules contain inactive enzyme precursors called zymogens, which are later activated to their active form to carry out specific functions.

The smooth ER is involved in the synthesis, processing, and packaging of zymogens into zymogen granules before their secretion. Here's how the smooth ER contributes to this process:

1. Synthesis of Zymogens: The smooth ER synthesizes zymogens by translating the mRNA into protein chains. These protein chains are then modified through processes like glycosylation and phosphorylation to form inactive enzyme precursors or zymogens.

2. Folding and Processing: The smooth ER provides an environment for proper folding and processing of zymogen proteins. Chaperone proteins present in the smooth ER lumen help in the correct folding of zymogens, ensuring their functional structure.

3. Transport and Packaging: Once the zymogens are properly folded and processed, they are transported to the Golgi apparatus via vesicular transport. The smooth ER is involved in packaging the zymogens into vesicles called zymogen granules.

4. Secretion of Zymogen Granules: The zymogen granules containing the packaged zymogens are then transported to the plasma membrane for secretion. Upon appropriate stimulation, these granules fuse with the plasma membrane, releasing their contents outside the cell.

Other Options:
- Lysosomes: Lysosomes are membrane-bound organelles involved in the degradation of cellular waste materials. They contain digestive enzymes and are not directly involved in the secretion of zymogen granules.
- Golgi Body: The Golgi apparatus is responsible for modifying, sorting, and packaging proteins for secretion or delivery to other cellular compartments. While it is involved in the processing of zymogens, it is not the primary organelle responsible for secreting zymogen granules.
- Sphaerosomes: Sphaerosomes are specialized organelles found in plant cells involved in the storage and metabolism of lipids. They are not directly involved in the secretion of zymogen granules.

Hence, the correct answer is option 'B' - Smooth Endoplasmic Reticulum (ER), as it plays a significant role in the synthesis, processing, and secretion of zymogen granules in cells.

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