Select the correct sequence about the life cycle of Plasmodium:a)Sporo...
The correct sequence of the Plasmodium life cycle involves the following steps:
Sporozoites are injected into humans by the female mosquito. The sporozoites travel to the liver where they mature. After the liver stage, the parasite enters the RBCs where it multiplies.Some of the parasites develop into gametocytes, which are released into the blood.These gametocytes are taken up by a female mosquito during a blood meal. Inside the mosquito, the gametocytes undergo sexual reproduction to form sporozoites.Finally, sporozoites are transmitted back to humans when the mosquito bites again.

Select the correct sequence about the life cycle of Plasmodium:a)Sporo...
Life Cycle of Plasmodium
The life cycle of Plasmodium, the parasite responsible for malaria, involves two hosts: humans and female Anopheles mosquitoes. The correct sequence of the life cycle is crucial for understanding malaria transmission.
Sporozoites in Humans
- Plasmodium enters the human body through the bite of an infected female mosquito, introducing sporozoites into the bloodstream.
Liver Cells
- The sporozoites travel to the liver, where they invade liver cells (hepatocytes) and undergo asexual reproduction, developing into merozoites.
RBCs (Red Blood Cells)
- Merozoites are released into the bloodstream and invade red blood cells, where they multiply further, leading to the clinical symptoms of malaria.
Gametocytes in Blood
- Some of these merozoites differentiate into gametocytes, which are the sexual forms of the parasite found in the blood.
Blood Meal by Female Mosquito
- When a female mosquito takes a blood meal from an infected human, she ingests these gametocytes.
Fertilization in Mosquito
- In the mosquito’s gut, gametocytes undergo fertilization, forming zygotes, which develop into ookinetes and then oocysts.
Sporozoites in Mosquito
- These oocysts multiply and eventually release sporozoites, which migrate to the mosquito's salivary glands, ready to infect another human when the mosquito bites again.
Conclusion
Option B accurately describes this life cycle by outlining the critical stages: sporozoites infect liver cells, move to RBCs, form gametocytes, are taken up by a mosquito, and finally develop back into sporozoites, completing the cycle.