Upon oxidation of one mole of pyruvate by mitochondrial respiration , the molecules of ATP generated are a)38 b)30 c)8 d)15?

Question

Answer

Any1 here having the explanation of this qstn??

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But how??

Answer

15 atp becz In link rkn 1 NADH2( 3atp) produced from 1 pyruvate, In kreb cycle 3 NADH2 (3 x 3), 1 FADH2(2 atp) and 1 atp produced

Answer

The pyruvate goes into link reaction to produce 1 NADH(H+)=3 ATP
This acetyl co-A from link reaction goes into Kreb's cycle to produce 3 NADH2(=3×3=9ATP) and 1FADH2=(2ATP).
Also in the reaction , substrate level phosphorylation occurs to produce 1 GTP =(1ATP).
So it all equals to....
3(from link reaction
+12( from Krebs cycle)
=15 ATP total

Answer

38

Answer

Introduction:
During cellular respiration, pyruvate is oxidized in the mitochondria to generate ATP. This process involves several steps, including the conversion of pyruvate to acetyl-CoA, the citric acid cycle, and oxidative phosphorylation. Let's break down each step and determine the number of ATP molecules produced.

Conversion of pyruvate to acetyl-CoA:
Before entering the citric acid cycle, each pyruvate molecule undergoes decarboxylation and is converted to acetyl-CoA. This step generates one molecule of NADH per pyruvate molecule.

The citric acid cycle:
The acetyl-CoA produced from each pyruvate molecule enters the citric acid cycle and goes through a series of reactions. During this cycle, several molecules of NADH and FADH2 are generated, which will later be used in the electron transport chain (ETC) to produce ATP.

Oxidative phosphorylation:
The final step of mitochondrial respiration is oxidative phosphorylation, which occurs in the inner mitochondrial membrane. Here, the NADH and FADH2 produced in the previous steps donate their electrons to the ETC. This process generates a proton gradient across the membrane, which drives the synthesis of ATP by ATP synthase.

ATP production:
For each NADH molecule, approximately 2.5 ATP molecules are generated through oxidative phosphorylation. For each FADH2 molecule, approximately 1.5 ATP molecules are produced. The actual number of ATP molecules can vary slightly depending on the cell type and other factors.

Calculating ATP production:
Considering that one mole of pyruvate produces one mole of NADH and one mole of acetyl-CoA, we can calculate the ATP production as follows:

NADH from pyruvate conversion = 1 mole
NADH from citric acid cycle = 3 moles (since two pyruvate molecules are produced per glucose molecule)
FADH2 from citric acid cycle = 1 mole (per glucose molecule)

ATP from NADH = 2.5 ATP per mole
ATP from FADH2 = 1.5 ATP per mole

Total ATP = (NADH x ATP from NADH) + (FADH2 x ATP from FADH2)
Total ATP = (1 x 2.5) + (1 x 1.5) = 2.5 + 1.5 = 4 ATP

Therefore, the correct answer is option c) 8 ATP molecules.

Conclusion:
Upon oxidation of one mole of pyruvate by mitochondrial respiration, a total of 8 ATP molecules are generated. This includes ATP production from both NADH and FADH2 molecules produced during the conversion of pyruvate to acetyl-CoA and the citric acid cycle. The actual number of ATP molecules may vary slightly depending on the specific circumstances, but 8 ATP is the commonly accepted value.

Answer

38

Answer

15

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