Basement membrane is composed ofa)Hyaluronic Acid + glycoproteinsb) On...
Basement membrane is composed of two layers, the basal lamina and the underlying layer of reticular connective tissue. ... The clear layer closer to the epithelium is called the lamina lucida, while the dense layer closer to the connective tissue is called the lamina densa.
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Basement membrane is composed ofa)Hyaluronic Acid + glycoproteinsb) On...
The correct answer is option 'A', which states that the basement membrane is composed of hyaluronic acid and glycoproteins.
The basement membrane is a specialized extracellular matrix that provides structural support and acts as a barrier between different tissue layers. It is found in various tissues and organs throughout the body, including the skin, blood vessels, kidneys, and lungs.
The composition of the basement membrane is complex and consists of several components, including proteins, glycoproteins, proteoglycans, and polysaccharides. Among these components, hyaluronic acid and glycoproteins play important roles in providing structural integrity and regulating cell behavior.
1. Hyaluronic Acid:
Hyaluronic acid is a large, negatively charged polysaccharide that is a major component of the basement membrane. It is composed of repeating units of disaccharides and is highly hydrophilic. Hyaluronic acid helps to maintain the hydration and viscosity of the basement membrane, allowing it to resist compression and provide a supportive environment for cells.
2. Glycoproteins:
Glycoproteins are proteins that are covalently linked to carbohydrates. They are abundant in the basement membrane and contribute to its structural stability and cell adhesion. Some of the important glycoproteins found in the basement membrane include laminins, collagen IV, nidogens, and perlecan. These glycoproteins form a complex network that provides structural support and regulates cell signaling and migration.
Laminins are a family of glycoproteins that play a crucial role in basement membrane organization. They form cross-links with collagen IV and other components, providing a scaffold for cell attachment and migration. Collagen IV is a major component of the basement membrane and forms a network that gives the membrane its tensile strength. Nidogens and perlecan are glycoproteins that help to stabilize the basement membrane and regulate cell behavior.
In conclusion, the correct answer is option 'A' because the basement membrane is composed of hyaluronic acid and glycoproteins, which are important for maintaining its structural integrity and regulating cell behavior.
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