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Which enzyme not require NAD as coenzyme–
  • a)
    Citrate synthetase
  • b)
    Pyruvate dehydrogenase
  • c)
    Succinate dehydrogenase
  • d)
    Alpha-ketoglutarate dehydrogenase
Correct answer is option 'A'. Can you explain this answer?
Verified Answer
Which enzyme not require NADas coenzyme–a)Citrate synthetaseb)Py...
The enzyme citrate synthase E.C. 2.3.3.1 (previously 4.1.3.7) exists in nearly all living cells and stands as a pace-making enzyme in the first step of the citric acid cycle (or Krebs cycle).Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix, but is encoded by nuclear DNA rather than mitochondrial. It is synthesized using cytoplasmic ribosomes, then transported into the mitochondrial matrix.
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Most Upvoted Answer
Which enzyme not require NADas coenzyme–a)Citrate synthetaseb)Py...
Citric synthetase is involved in condensation process...oxaloacetic acid +Acetyl CoA ...gives.,..citric acid +Coenzyme A ...in presence of citric synthetase........while NAD is required in oxidation reactions...1)Isocitric acid + NAD..gives.. Oxalosuccinic acid +NADH....in presence of isocitric dehydrogenase enzyme. 2)alpha-Ketoglutaric acid +NAD +CoA..gives.. Succinyl CoA +NADH +Co2....in presence of alpha-Ketoglutaric dehydrogenase.while in third oxidation.,Succinic acid+FAD...gives...Fumaric acid +FADH2...in presence of succinic dehydrogenase.
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Which enzyme not require NADas coenzyme–a)Citrate synthetaseb)Pyruvate dehydrogenasec)Succinate dehydrogenased)Alpha-ketoglutarate dehydrogenaseCorrect answer is option 'A'. Can you explain this answer?
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