Mark the incorrect statement in context to O2 binding to Hb(1)high pH ...
O2 binding to Hb occurs in the following conditions:
1) lower temperature,
2) lower pCO2
3) higher pO2
4) high pH
5) low H+ concentration.
So none of the options r correct.All the conditions given are appropriate for O2 binding.
Mark the incorrect statement in context to O2 binding to Hb(1)high pH ...
**Incorrect Statement Regarding O2 Binding to Hb**
The incorrect statement in context to O2 binding to Hb is "higher pO2".
**Explanation:**
Oxygen (O2) binds to hemoglobin (Hb) in the red blood cells to be transported to different tissues in the body. The binding of O2 to Hb is dependent on various factors such as pH, temperature, and partial pressure of O2 (pO2) and carbon dioxide (pCO2).
(1) High pH: At high pH, Hb has a higher affinity for O2, meaning it binds more easily to O2. This is due to the fact that high pH indicates a lower concentration of hydrogen ions (H+), which compete with O2 for binding to Hb. Therefore, the correct statement is that at high pH, O2 binding to Hb is facilitated.
(2) Low temperature: At low temperature, Hb also has a higher affinity for O2, as the binding of O2 to Hb is an exothermic process. This means that heat is released when O2 binds to Hb, so at lower temperatures, there is less thermal energy available to overcome the binding energy of O2 and Hb. Therefore, the correct statement is that at low temperature, O2 binding to Hb is facilitated.
(3) Lower pCO2: At lower pCO2, Hb has a higher affinity for O2, as CO2 competes with O2 for binding to Hb. When pCO2 is high, Hb binds to CO2 and releases O2 in the tissues. Therefore, the correct statement is that at lower pCO2, O2 binding to Hb is facilitated.
(4) Lower pO2: At lower pO2, Hb has a lower affinity for O2, as there is less O2 available to bind to Hb. This is because the binding of O2 to Hb is a cooperative process, meaning that the binding of the first O2 molecule to Hb increases the affinity of Hb for subsequent O2 molecules. Therefore, the correct statement is that at lower pO2, O2 binding to Hb is hindered.
In conclusion, the incorrect statement in context to O2 binding to Hb is "higher pO2". The correct statement is that at lower pO2, O2 binding to Hb is hindered.
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