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Removal of calcium from freshly collected blood would [1989]
  • a)
    cause delayed clotting
  • b)
    prevent clotting
  • c)
    cause immediate clotting
  • d)
    prevent destruction of haemoglobin
Correct answer is option 'B'. Can you explain this answer?
Verified Answer
Removal of calcium from freshly collected blood would [1989]a)cause de...
Thromboplastin, a lipoprotein, helps in clot formation. Thromboplastin helps in the formation of an enzyme prothrombinase. This enzyme inactivates heparin and it also converts the inactive plasma protein prothrombin into its active form, thrombin. Both the changes require calcium ions. Thrombin converts fibrinogen molecule to insoluble fibrin.
The fibrin monomers polymerize to form long, sticky fibres. The fibrin threads form a fine network over the wound and trap blood corpuscles (RBCs, WBCs, platelets) to form a crust, the clot. Thus, if calcium is removed from the blood, clotting process will not occur.
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Removal of calcium from freshly collected blood would [1989]a)cause delayed clottingb)prevent clottingc)cause immediate clottingd)prevent destruction of haemoglobinCorrect answer is option 'B'. Can you explain this answer?
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