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In a population an autosomal recessive disorder is present in 60 individual out of 6000. What is the no. Of homozygous normal offspring in population?
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In a population an autosomal recessive disorder is present in 60 indiv...
Calculation of Homozygous Normal Offspring in a Population


Given Information:


  • Autosomal recessive disorder is present in 60 individuals out of 6000.



Calculating the Frequency of the Recessive Allele:


  • The frequency of the recessive allele (q) can be calculated using the formula: q = sqrt(60/6000) = 0.1



Calculating the Frequency of the Dominant Allele:


  • The frequency of the dominant allele (p) can be calculated using the formula: p = 1 - q = 0.9



Calculating the No. of Homozygous Normal Offspring:


  • The frequency of homozygous normal individuals (AA) can be calculated using the formula: p^2 = (0.9)^2 = 0.81

  • The total number of individuals in the population is 6000.

  • Therefore, the number of homozygous normal individuals in the population can be calculated using the formula: 6000 x 0.81 = 4860

  • Hence, there are 4860 homozygous normal offspring in the population.



Therefore, the number of homozygous normal offspring in a population can be calculated using the frequency of the dominant and recessive alleles and the total number of individuals in the population.
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In a population an autosomal recessive disorder is present in 60 indiv...
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In a population an autosomal recessive disorder is present in 60 individual out of 6000. What is the no. Of homozygous normal offspring in population?
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