A copy of the input also goes directly to the deep cerebellar nuclei. Granule cells are extremely small and extremely numerous. ... The only way out of cerebellar cortex is given by Purkinje cell axons, which make inhibitory connections with neurons in the deep cerebellar nuclei.

Purkinje’s cells are most complex neurons of Cerebellum.

Explanation:
Purkinje cells are large, multipolar neurons located in the cerebellar cortex of the brain. They are named after Jan Evangelista Purkyně, a Czech anatomist who first described them in 1837. Purkinje cells are the most complex neurons in the cerebellum and play a crucial role in motor coordination, learning, and memory.

Structure:
• Purkinje cells have a large, fan-shaped dendritic arbor that extends into the molecular layer of the cerebellar cortex.
• The dendrites of Purkinje cells are covered in small spines, which receive input from parallel fibers and climbing fibers.
• The axon of Purkinje cells projects to the deep cerebellar nuclei, which relay motor output to the rest of the brain.

Function:
• Purkinje cells play a critical role in motor coordination by integrating input from parallel fibers and climbing fibers to modulate the activity of the deep cerebellar nuclei.
• Purkinje cells are also involved in learning and memory, as they can undergo plastic changes in response to sensory input and motor output.
• Purkinje cell dysfunction is associated with a range of neurological disorders, including ataxia, tremor, and dystonia.

Conclusion:
In conclusion, Purkinje cells are the most complex neurons of the cerebellum and play a vital role in motor coordination, learning, and memory. Dysfunction of Purkinje cells can lead to a range of neurological disorders, highlighting their importance in brain function.