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Substrate concentration at which an enzyme attains
half its maximum velocity is
- a)Threshold value
- b)Half life
- c)Michaelis-Menten coeffiecient
- d)Concentration coeffiecient
Correct answer is option 'C'. Can you explain this answer?
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Substrate concentration at which an enzyme attainshalf its maximum vel...
A small Km indicates that the enzyme requires only a small amount of substrate to become saturated. Hence, the maximum velocity is reached at relatively low substrate concentrations. A large Km indicates the need for high substrate concentrations to achieve maximum reaction velocity.
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Substrate concentration at which an enzyme attainshalf its maximum vel...
Michaelis-Menten coefficient (km) is a constant indicating substrate concentration at which an enzyme catalysed reaction attains half of its maximum velocity. Lower the km value greater will be speed of catalysed reaction. and higher will be the rate of substrate formation.
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Substrate concentration at which an enzyme attainshalf its maximum vel...
Michaelis-Menten Coefficient Explanation:
The substrate concentration at which an enzyme attains half its maximum velocity is known as the Michaelis-Menten coefficient. This coefficient is a crucial parameter in enzyme kinetics and is denoted by Km.
Michaelis-Menten Equation:
The Michaelis-Menten equation describes the relationship between the rate of an enzyme-catalyzed reaction and the substrate concentration. It is given by:
\[V = \dfrac{V_{max} \times [S]}{K_m + [S]}\]
where:
- V is the reaction rate,
- Vmax is the maximum reaction rate,
- [S] is the substrate concentration,
- Km is the Michaelis-Menten coefficient.
Significance of Km:
Km is an important parameter as it indicates the affinity of an enzyme for its substrate. A lower Km value indicates high affinity, meaning the enzyme can achieve half of its maximum velocity at a lower substrate concentration. Conversely, a higher Km value indicates lower affinity, requiring a higher substrate concentration to reach half of the maximum velocity.
Threshold Value and Half-Life:
- Threshold value refers to the minimum value required to initiate a response, which is different from Km.
- Half-life is the time taken for the concentration of a substance to decrease to half its initial value, not related to enzyme kinetics.
Therefore, the correct answer to the question is the Michaelis-Menten coefficient, which represents the substrate concentration at which an enzyme attains half of its maximum velocity.
The substrate concentration at which an enzyme attains half its maximum velocity is known as the Michaelis-Menten coefficient. This coefficient is a crucial parameter in enzyme kinetics and is denoted by Km.
Michaelis-Menten Equation:
The Michaelis-Menten equation describes the relationship between the rate of an enzyme-catalyzed reaction and the substrate concentration. It is given by:
\[V = \dfrac{V_{max} \times [S]}{K_m + [S]}\]
where:
- V is the reaction rate,
- Vmax is the maximum reaction rate,
- [S] is the substrate concentration,
- Km is the Michaelis-Menten coefficient.
Significance of Km:
Km is an important parameter as it indicates the affinity of an enzyme for its substrate. A lower Km value indicates high affinity, meaning the enzyme can achieve half of its maximum velocity at a lower substrate concentration. Conversely, a higher Km value indicates lower affinity, requiring a higher substrate concentration to reach half of the maximum velocity.
Threshold Value and Half-Life:
- Threshold value refers to the minimum value required to initiate a response, which is different from Km.
- Half-life is the time taken for the concentration of a substance to decrease to half its initial value, not related to enzyme kinetics.
Therefore, the correct answer to the question is the Michaelis-Menten coefficient, which represents the substrate concentration at which an enzyme attains half of its maximum velocity.
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Substrate concentration at which an enzyme attainshalf its maximum velocity isa)Threshold valueb)Half lifec)Michaelis-Menten coeffiecientd)Concentration coeffiecientCorrect answer is option 'C'. Can you explain this answer?
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