Those with molecular weight less than 1000 Dalton are called macromolecules or biomolecules.. And these form Acid soluble fraction.......

Understanding Biomolecules and Their Molecular Weights
Biomolecules are essential for all forms of life and can be classified into four main categories: carbohydrates, proteins, lipids, and nucleic acids. Each class has unique structures, functions, and molecular weights.
1. Carbohydrates
- Composed of carbon, hydrogen, and oxygen.
- Common examples include glucose and starch.
- Molecular weight varies:
- Glucose (C6H12O6) has a molecular weight of approximately 180 g/mol.
- Starch, being a polysaccharide, can have a much higher molecular weight ranging from thousands to millions of g/mol.
2. Proteins
- Made up of amino acids linked by peptide bonds.
- The molecular weight of proteins varies significantly:
- Small proteins like insulin have a molecular weight of about 5,800 g/mol.
- Larger proteins, such as titin, can exceed 3 million g/mol.
3. Lipids
- Composed mainly of fatty acids and glycerol.
- Molecular weights can vary:
- Common triglycerides can range from 800 to over 1,000 g/mol.
- Cholesterol, a type of lipid, has a molecular weight of approximately 386 g/mol.
4. Nucleic Acids
- DNA and RNA are polymers made of nucleotides.
- Molecular weights also vary:
- A single nucleotide has a molecular weight ranging from 300 to 400 g/mol.
- DNA molecules can weigh millions of g/mol depending on their length.
Conclusion
Understanding the molecular weights of biomolecules is crucial as it helps in determining their roles and interactions within biological systems. Each biomolecule contributes to the complexity of life, and their varying weights reflect their diverse functions.