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Which one is not a preparatory phase or energy spending phase of Glycoloysis
- a)Synthesis of fructose 6-phosphate
- b)Phosphorylation of glucose
- c)Formation of Pyruvate
- d)Isomerisation of DiHAP
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Which one is not a preparatory phase or energy spending phase of Glyco...
Formation of pyruvate is not a prerparatory phase or energy spending phase of Glycolysis. In this phase one ATP molecule is released.
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Which one is not a preparatory phase or energy spending phase of Glyco...
Explanation:
Glycolysis is the metabolic pathway that converts glucose into pyruvate. It is a multi-step process that occurs in the cytoplasm of cells. Glycolysis can be divided into two phases: preparatory phase and energy-yielding phase.
Preparatory Phase:
The preparatory phase of glycolysis involves the conversion of glucose to fructose 1,6-bisphosphate. It requires the input of two ATP molecules and includes the following steps:
1. Phosphorylation of glucose: Glucose is phosphorylated to glucose-6-phosphate by adding a phosphate group from ATP. This step is catalyzed by the enzyme hexokinase.
2. Isomerisation of glucose-6-phosphate: Glucose-6-phosphate is converted to its isomer, fructose-6-phosphate, by the enzyme phosphohexose isomerase.
3. Phosphorylation of fructose-6-phosphate: Fructose-6-phosphate is phosphorylated to fructose 1,6-bisphosphate by adding a second phosphate group from ATP. This step is catalyzed by the enzyme phosphofructokinase.
Energy-Yielding Phase:
The energy-yielding phase of glycolysis involves the conversion of fructose 1,6-bisphosphate to pyruvate. It generates ATP and NADH and includes the following steps:
4. Cleavage of fructose 1,6-bisphosphate: Fructose 1,6-bisphosphate is cleaved into two three-carbon molecules, dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P), by the enzyme aldolase.
5. Isomerisation of dihydroxyacetone phosphate: DHAP is converted to G3P by the enzyme triose phosphate isomerase.
6. Oxidation and phosphorylation of glyceraldehyde 3-phosphate: G3P is oxidized by the enzyme glyceraldehyde 3-phosphate dehydrogenase, generating NADH. The oxidized G3P is then phosphorylated by the enzyme phosphoglycerate kinase, generating ATP and 1,3-bisphosphoglycerate.
7. Conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate: 1,3-bisphosphoglycerate is converted to 3-phosphoglycerate by the enzyme phosphoglycerate mutase.
8. Conversion of 3-phosphoglycerate to 2-phosphoglycerate: 3-phosphoglycerate is converted to 2-phosphoglycerate by the enzyme enolase.
9. Conversion of 2-phosphoglycerate to phosphoenolpyruvate: 2-phosphoglycerate is converted to phosphoenolpyruvate (PEP) by the enzyme pyruvate kinase, generating ATP.
10. Conversion of PEP to pyruvate: PEP is converted to pyruvate by the enzyme pyruvate kinase, generating ATP.
Conclusion:
The formation of pyruvate is not a preparatory phase or energy spending phase of glycolysis. It is the end product of glycolysis and is generated during the energy-yielding phase of the pathway.
Glycolysis is the metabolic pathway that converts glucose into pyruvate. It is a multi-step process that occurs in the cytoplasm of cells. Glycolysis can be divided into two phases: preparatory phase and energy-yielding phase.
Preparatory Phase:
The preparatory phase of glycolysis involves the conversion of glucose to fructose 1,6-bisphosphate. It requires the input of two ATP molecules and includes the following steps:
1. Phosphorylation of glucose: Glucose is phosphorylated to glucose-6-phosphate by adding a phosphate group from ATP. This step is catalyzed by the enzyme hexokinase.
2. Isomerisation of glucose-6-phosphate: Glucose-6-phosphate is converted to its isomer, fructose-6-phosphate, by the enzyme phosphohexose isomerase.
3. Phosphorylation of fructose-6-phosphate: Fructose-6-phosphate is phosphorylated to fructose 1,6-bisphosphate by adding a second phosphate group from ATP. This step is catalyzed by the enzyme phosphofructokinase.
Energy-Yielding Phase:
The energy-yielding phase of glycolysis involves the conversion of fructose 1,6-bisphosphate to pyruvate. It generates ATP and NADH and includes the following steps:
4. Cleavage of fructose 1,6-bisphosphate: Fructose 1,6-bisphosphate is cleaved into two three-carbon molecules, dihydroxyacetone phosphate (DHAP) and glyceraldehyde 3-phosphate (G3P), by the enzyme aldolase.
5. Isomerisation of dihydroxyacetone phosphate: DHAP is converted to G3P by the enzyme triose phosphate isomerase.
6. Oxidation and phosphorylation of glyceraldehyde 3-phosphate: G3P is oxidized by the enzyme glyceraldehyde 3-phosphate dehydrogenase, generating NADH. The oxidized G3P is then phosphorylated by the enzyme phosphoglycerate kinase, generating ATP and 1,3-bisphosphoglycerate.
7. Conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate: 1,3-bisphosphoglycerate is converted to 3-phosphoglycerate by the enzyme phosphoglycerate mutase.
8. Conversion of 3-phosphoglycerate to 2-phosphoglycerate: 3-phosphoglycerate is converted to 2-phosphoglycerate by the enzyme enolase.
9. Conversion of 2-phosphoglycerate to phosphoenolpyruvate: 2-phosphoglycerate is converted to phosphoenolpyruvate (PEP) by the enzyme pyruvate kinase, generating ATP.
10. Conversion of PEP to pyruvate: PEP is converted to pyruvate by the enzyme pyruvate kinase, generating ATP.
Conclusion:
The formation of pyruvate is not a preparatory phase or energy spending phase of glycolysis. It is the end product of glycolysis and is generated during the energy-yielding phase of the pathway.
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Which one is not a preparatory phase or energy spending phase of Glyco...
Glycolysis Is divided into preparatory phase and pay off phase
preparatory phase is upto splitting of fructose_1_6 di p into PGAL and DHAP
that onwards I'd pay off phase,formation of pyruvate is the last step hence falls into the pay off phase
preparatory phase is upto splitting of fructose_1_6 di p into PGAL and DHAP
that onwards I'd pay off phase,formation of pyruvate is the last step hence falls into the pay off phase
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