Necleotide in m-RNA are always linked together by phospho -ester bonds. depending on the number of nucleotides it calls phospho_ di , tri , ... polyester etc.

Nucleotide Bonding in mRNA

Nucleotides in mRNA are linked to one another by phosphodiester bonds. These bonds are formed between the phosphate group of one nucleotide and the hydroxyl group of another nucleotide, creating a chain-like structure.

Phosphodiester Bonds

- Phosphodiester bonds are covalent bonds that form between the phosphate group of one nucleotide and the sugar group of another nucleotide.
- These bonds are crucial for the stability and integrity of the mRNA molecule, as they create a strong backbone for the nucleotide sequence.
- The formation of phosphodiester bonds requires the removal of a water molecule, a process known as dehydration synthesis.
- The sequence of nucleotides linked by phosphodiester bonds determines the genetic code carried by the mRNA molecule.

In contrast, hydrogen bonds are important in maintaining the secondary structure of mRNA, such as base pairing between complementary nucleotides. Hydrophobic bonds are involved in the folding of mRNA into its tertiary structure, while glycosidic bonds are primarily found in nucleic acids like DNA and RNA, linking the base to the sugar molecule. However, in mRNA, the primary linkage between nucleotides is through phosphodiester bonds.