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All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is [2007]
  • a)
    isocitrate dehydrogenase
  • b)
    malate dehydrogenase
  • c)
    succinate dehydrogenase
  • d)
    lactate dehydrogenase.
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
All enzymes of TCA cycle are located in the mitochondrial matrix excep...
Succinate dehydrogenase enzyme is present on inner membrane of mitochondria and catalysed the oxidation of succinate to fumarate.
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All enzymes of TCA cycle are located in the mitochondrial matrix excep...
Location of Succinate Dehydrogenase
Succinate dehydrogenase is the only enzyme of the TCA cycle that is not located in the mitochondrial matrix. In eukaryotes, it is found in the inner mitochondrial membranes, while in prokaryotes, it is located in the cytosol.

Function of Succinate Dehydrogenase
Succinate dehydrogenase plays a crucial role in the TCA cycle by catalyzing the oxidation of succinate to fumarate. It also participates in the electron transport chain by transferring electrons to ubiquinone.

Role in Cellular Respiration
As part of the TCA cycle and the electron transport chain, succinate dehydrogenase is essential for the generation of ATP through oxidative phosphorylation. It helps in the production of energy in the form of ATP, which is used by the cell for various metabolic processes.

Significance in Eukaryotes and Prokaryotes
The localization of succinate dehydrogenase in the inner mitochondrial membranes of eukaryotes and in the cytosol of prokaryotes reflects the evolutionary differences between these two types of organisms. Despite the difference in location, the enzyme serves the same fundamental function in both eukaryotic and prokaryotic cells.
In summary, succinate dehydrogenase is a key enzyme in the TCA cycle that is unique in its location within the cell. Its presence in the inner mitochondrial membranes of eukaryotes and in the cytosol of prokaryotes highlights its importance in cellular respiration and energy production.
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All enzymes of TCA cycle are located in the mitochondrial matrix excep...
Succinate:ubiquinone oxidoreductase, also known in mitochondria as Complex II, provides a link between the citric acid cycle and the membrane-bound electrontransport system. The membrane extrinsic, water-soluble domain, known as succinate dehydrogenase (SDH), contains the fumarate/succinate active site with a covalently bound FAD group and three iron-sulfur clusters:[2Fe-2S]2 +/1+, [4Fe-4S]2+/1+, and [3Fe-4S]1 +/0 . The enzyme catalyzes the interconversion of fumarate and succinate, and is closely related to fumarate reductase
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All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is [2007]a)isocitrate dehydrogenaseb)malate dehydrogenasec)succinate dehydrogenased)lactate dehydrogenase.Correct answer is option 'C'. Can you explain this answer?
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All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is [2007]a)isocitrate dehydrogenaseb)malate dehydrogenasec)succinate dehydrogenased)lactate dehydrogenase.Correct answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is [2007]a)isocitrate dehydrogenaseb)malate dehydrogenasec)succinate dehydrogenased)lactate dehydrogenase.Correct answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is [2007]a)isocitrate dehydrogenaseb)malate dehydrogenasec)succinate dehydrogenased)lactate dehydrogenase.Correct answer is option 'C'. Can you explain this answer?.
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