**Explanation:**

In Buddhist philosophy, the term "Anicca" refers to the concept of impermanence or transience. It is one of the three characteristics of existence, along with "Dukkha" (suffering) and "Anatta" (non-self). Anicca is a fundamental principle in Buddhism and plays a crucial role in understanding the nature of reality.

**1. Impermanence and the Universe:**
Anicca suggests that all things in the universe are subject to change and are impermanent. This includes not only material objects but also mental and emotional states, relationships, and even the universe itself. According to Buddhism, everything that arises is bound to cease or change eventually.

**2. The Nature of Existence:**
The concept of Anicca challenges the belief in a permanent, unchanging self or soul. It suggests that there is no fixed, unchanging essence or substance underlying our existence. Instead, everything is in a state of flux and constantly changing.

**3. Transience and Suffering:**
Anicca is closely related to the concept of Dukkha (suffering). The Buddhist belief is that attachment and clinging to impermanent things lead to suffering. When we crave for things to be permanent or try to hold onto them, we experience dissatisfaction and disappointment when they inevitably change or disappear.

**4. Impermanence and Liberation:**
Understanding and accepting the impermanence of all things is seen as a path to liberation and freedom from suffering. By realizing the transitory nature of existence, individuals can cultivate a sense of detachment and non-attachment, which leads to a state of peace and equanimity.

**Conclusion:**
In Buddhist philosophy, "Anicca" refers to the impermanence and transience of all things in the universe. It challenges the belief in a permanent self and emphasizes the importance of understanding and accepting change as a means to liberation from suffering. By recognizing and embracing the transient nature of existence, individuals can cultivate a deeper sense of wisdom, compassion, and peace.