Which of the following statements is not correct about penicillin?a)Pe...
Explanation:
Penicillin is a group of antibiotics that are derived from the antibacterial fungus Penicillium. It was the first widely used antibiotic and has played a significant role in treating bacterial infections. However, one of the statements is not correct about penicillin, which is option D - "It has bacteriostatic effect."
Penicillin G has a narrow spectrum:
Penicillin G is a type of penicillin that has a narrow spectrum of activity. It is effective against Gram-positive bacteria, including Streptococcus pneumoniae, Streptococcus pyogenes, and many strains of Staphylococcus aureus. However, it is not effective against Gram-negative bacteria.
Penicillin is extracted from antibacterial fungus Penicillium:
Penicillin is produced by the fungus Penicillium through a process of fermentation. Alexander Fleming, the discoverer of penicillin, observed that the fungus inhibited the growth of bacteria, leading to the extraction and purification of the antibiotic compound.
Ampicillin and amoxicillin are synthetic modifications of penicillins:
Ampicillin and amoxicillin are semi-synthetic modifications of penicillins. They are created by adding different side chains to the penicillin molecule, which enhances their spectrum of activity and stability against acid degradation. These modifications allow them to be effective against a broader range of bacteria, including some Gram-negative bacteria.
Penicillin does not have a bacteriostatic effect:
The incorrect statement in the options is that penicillin has a bacteriostatic effect. In reality, penicillin has a bactericidal effect, meaning it kills bacteria rather than inhibiting their growth. It achieves this by interfering with the synthesis of the bacterial cell wall, leading to cell lysis and death. This bactericidal effect is one of the reasons why penicillin is highly effective in treating bacterial infections.
In conclusion, the correct statement about penicillin is that it has a bactericidal effect, not a bacteriostatic effect.
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