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What is/are true regarding Fischer projection of an optically active isomer?
  • a)
    Interchange of two groups position at chiral centre changes the relative configuration
  • b)
    Interchange of two groups position at chiral centre changes the absolute configuration 
  • c)
     Rotation of Fischer projection any way but by 180° does not change the configuration at chiral centre
  • d)
     Reaction involving breaking of bonds to chiral centre always changes the sign of optical rotation  
Correct answer is option 'A,B'. Can you explain this answer?
Most Upvoted Answer
What is/are true regarding Fischer projection of an optically active i...

In Fischer's projection, the four bonds of a chiral carbon are represented by a cross with the carbon atom at the intersection of the horizontal and vertical lines.
The two horizontal bonds are directed toward the viewer (forward of the stereogenic carbon), while the two vertical bonds are directed behind the central carbon (away from the viewer)
.
Now, coming to the options, option ‘a’ is correct because the interchange of two groups’ positions at the chiral center changes the relative configuration of the molecule
.
Option ‘b’ is also correct because the interchange of two groups’ positions at the chiral center changes the absolute configuration of the molecule
.
Option ‘c’ is incorrect because the rotation of Fischer projection by 180� changes the configuration at the chiral center
.
Option ‘d’ is incorrect because the reaction involving the breaking of bonds to the chiral center does not always change the sign of optical rotation
.

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Community Answer
What is/are true regarding Fischer projection of an optically active i...
A) Interchange of two groups position at chiral centre changes the relative configuration

b) Interchange of two groups position at chiral centre does not change the absolute configuration

c) Rotation of Fischer projection by 180 degrees changes the absolute configuration
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What is/are true regarding Fischer projection of an optically active isomer?a)Interchange of two groups position at chiral centre changes the relative configurationb)Interchange of two groups position at chiral centre changes the absolute configurationc)Rotation of Fischer projection any way but by 180° does not change the configuration at chiral centred)Reaction involving breaking of bonds to chiral centre always changes the sign of optical rotationCorrect answer is option 'A,B'. Can you explain this answer?
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What is/are true regarding Fischer projection of an optically active isomer?a)Interchange of two groups position at chiral centre changes the relative configurationb)Interchange of two groups position at chiral centre changes the absolute configurationc)Rotation of Fischer projection any way but by 180° does not change the configuration at chiral centred)Reaction involving breaking of bonds to chiral centre always changes the sign of optical rotationCorrect answer is option 'A,B'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about What is/are true regarding Fischer projection of an optically active isomer?a)Interchange of two groups position at chiral centre changes the relative configurationb)Interchange of two groups position at chiral centre changes the absolute configurationc)Rotation of Fischer projection any way but by 180° does not change the configuration at chiral centred)Reaction involving breaking of bonds to chiral centre always changes the sign of optical rotationCorrect answer is option 'A,B'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for What is/are true regarding Fischer projection of an optically active isomer?a)Interchange of two groups position at chiral centre changes the relative configurationb)Interchange of two groups position at chiral centre changes the absolute configurationc)Rotation of Fischer projection any way but by 180° does not change the configuration at chiral centred)Reaction involving breaking of bonds to chiral centre always changes the sign of optical rotationCorrect answer is option 'A,B'. Can you explain this answer?.
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