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Concentration of urine occurs in which segment of the nephron?
  • a)
    Proximal convoluted tubule
  • b)
    Distal convoluted tubule
  • c)
    Glomerulus
  • d)
    Loop of Henle
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
Concentration of urine occurs in which segment of the nephron?a)Proxi...
Counter-current mechanism: The osmotic medullary gradient is mainly developed due to NaCl and urea.
A. Movement of NaCl: Ascending limb of Henle’s loop → Descending limb of vasa recta → Ascending limb of vasa recta → Interstitium.
B. Movement of Urea: Thin segment of the ascending limb of Henle’s loop → Collecting tubule → Interstitium.
The transport of these substances becomes possible only because of the special arrangement of Henle’s loop and vasa recta, which is termed as a counter-current mechanism. The development of such medullary interstitium facilitates the movement of water from the collecting tubule thus making the urine nearly 4 times concentrated than the initial filtrate formed.
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Concentration of urine occurs in which segment of the nephron?a)Proximal convoluted tubuleb)Distal convoluted tubulec)Glomerulusd)Loop of HenleCorrect answer is option 'D'. Can you explain this answer?
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