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Select the correctly matched pair
  • a)
    Cystic fibrosis : X-linked recessive
  • b)
    Phenylketonuria : Autosomal dominant
  • c)
    Myotonic dystrophy : Autosomal recessive
  • d)
    Sickle-cell anaemia : Autosomal recessive
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
Select the correctly matched paira)Cystic fibrosis : X-linked recessi...
1. Cystic fibrosis, phenylketonuria and sicklecell anaemia are autosomal recessive traits.
2. Myotonic dystrophy is a autosomal dominant trait.
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Community Answer
Select the correctly matched paira)Cystic fibrosis : X-linked recessi...
Explanation:

Sickle-cell anaemia : Autosomal recessive
Sickle-cell anaemia is a genetic disorder caused by a mutation in the HBB gene, which is inherited in an autosomal recessive pattern. This means that an individual must inherit two copies of the mutated gene (one from each parent) in order to have the disease.
- The HBB gene provides instructions for making a protein called beta-globin, which is a component of hemoglobin. The mutation in the gene leads to the production of abnormal hemoglobin molecules, causing red blood cells to become stiff and sickle-shaped.
- Individuals with sickle-cell anaemia may experience symptoms such as anemia, pain crises, organ damage, and increased risk of infections.
Therefore, the correct pairing is Sickle-cell anaemia : Autosomal recessive.
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Select the correctly matched paira)Cystic fibrosis : X-linked recessiveb)Phenylketonuria : Autosomal dominantc)Myotonic dystrophy : Autosomal recessived)Sickle-cell anaemia : Autosomal recessiveCorrect answer is option 'D'. Can you explain this answer?
Question Description
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