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A heterozygous female, i.e., a carrier for haemophilia marries a normal male. The chances in the progeny of being diseased is for
  • a)
    All offsprings
  • b)
    All daughters
  • c)
    Some of their daughters
  • d)
    Some of their sons
Correct answer is option 'D'. Can you explain this answer?
Most Upvoted Answer
A heterozygous female, i.e., a carrier for haemophilia marries a norm...
Explanation:

Genetic Inheritance of Haemophilia:
- Haemophilia is a genetic disorder caused by a mutation in the gene responsible for producing clotting factors.
- It is an X-linked recessive disorder, which means the gene responsible is located on the X chromosome.

Genotype of Parents:
- The female is a carrier for haemophilia, which means she carries one normal allele (X^H) and one mutated allele (X^h) on her X chromosomes.
- The male is normal, with two normal alleles (X^H Y).

Genetic Possibilities in Offspring:
- When the carrier female and the normal male have offspring, the possible genotypes of the children are as follows:
- Sons: X^H Y (normal) or X^h Y (affected)
- Daughters: X^H X^H (normal), X^H X^h (carrier), X^h X^h (affected)

Chances of Diseased Offspring:
- Since the female is a carrier, there is a 50% chance that she will pass on the mutated allele to her sons.
- Therefore, some of their sons (50% chance) have the potential to be affected by haemophilia.

Conclusion:
- In this scenario, the chances of some of their sons being diseased with haemophilia are higher than all offspring or all daughters.
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Community Answer
A heterozygous female, i.e., a carrier for haemophilia marries a norm...
1. Haemophilia is a sex-linked recessive disease
2. It can be transmitted from unaffected carrier female to some of the male progeny.
3. The possibility of a female becoming a haemophilic is extremely rare.
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A heterozygous female, i.e., a carrier for haemophilia marries a normal male. The chances in the progeny of being diseased is fora)All offspringsb)All daughtersc)Some of their daughtersd)Some of their sonsCorrect answer is option 'D'. Can you explain this answer?
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