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Antigenic determinant sites bind to which portion of an antibody molecule?
(1) Light chain
(2) Heavy chain
(3) Intermediate chains
(4) Plasma cells
(1) Light chain
(2) Heavy chain
(3) Intermediate chains
(4) Plasma cells
- a)1 and 2 are correct
- b)2 and 4 are correct
- c)1, 2, 3 are correct
- d)1 and 3 are correct
Correct answer is 'A'. Can you explain this answer?
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Verified Answer
Antigenic determinant sites bind to which portion of an antibody molec...
In light and heavy chain the specific region on an antigen that an antibody recognizes and binds to is called the epitope or antigenic determinant. An epitope is usually 5-8 amino acids long on the surface of the protein.
Most Upvoted Answer
Antigenic determinant sites bind to which portion of an antibody molec...
Antigenic determinant sites, also known as epitopes, are the specific regions on an antigen to which antibodies bind. Antibodies, also called immunoglobulins, are Y-shaped proteins produced by plasma cells in response to the presence of antigens.
Antibodies are composed of four protein chains: two identical heavy chains and two identical light chains. Each chain consists of constant and variable regions. The variable regions are responsible for antigen binding.
To understand which portion of an antibody molecule antigenic determinant sites bind to, let's break down the options provided:
1) Light chain: The light chain is a smaller protein chain that is located on one side of the Y-shaped antibody molecule. It consists of a constant region and a variable region. The variable region of the light chain is involved in antigen binding. Therefore, option 1 is correct.
2) Heavy chain: The heavy chain is a larger protein chain that is located on the other side of the Y-shaped antibody molecule. It also consists of a constant region and a variable region. The variable region of the heavy chain is also involved in antigen binding. Therefore, option 2 is correct.
3) Intermediate chains: Intermediate chains are not part of the structure of an antibody molecule. They are not involved in antigen binding. Therefore, option 3 is incorrect.
4) Plasma cells: Plasma cells are the cells that produce antibodies. They are not directly involved in antigen binding. Therefore, option 4 is incorrect.
Based on the above analysis, options 1 and 2 are correct, as antigenic determinant sites bind to both the light chain and the heavy chain of an antibody molecule. Therefore, the correct answer is option A.
Antibodies are composed of four protein chains: two identical heavy chains and two identical light chains. Each chain consists of constant and variable regions. The variable regions are responsible for antigen binding.
To understand which portion of an antibody molecule antigenic determinant sites bind to, let's break down the options provided:
1) Light chain: The light chain is a smaller protein chain that is located on one side of the Y-shaped antibody molecule. It consists of a constant region and a variable region. The variable region of the light chain is involved in antigen binding. Therefore, option 1 is correct.
2) Heavy chain: The heavy chain is a larger protein chain that is located on the other side of the Y-shaped antibody molecule. It also consists of a constant region and a variable region. The variable region of the heavy chain is also involved in antigen binding. Therefore, option 2 is correct.
3) Intermediate chains: Intermediate chains are not part of the structure of an antibody molecule. They are not involved in antigen binding. Therefore, option 3 is incorrect.
4) Plasma cells: Plasma cells are the cells that produce antibodies. They are not directly involved in antigen binding. Therefore, option 4 is incorrect.
Based on the above analysis, options 1 and 2 are correct, as antigenic determinant sites bind to both the light chain and the heavy chain of an antibody molecule. Therefore, the correct answer is option A.
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Antigenic determinant sites bind to which portion of an antibody molecule?(1) Light chain(2) Heavy chain(3) Intermediate chains(4) Plasma cellsa)1 and 2 are correctb)2 and 4 are correctc)1, 2, 3 are correctd)1 and 3 are correctCorrect answer is 'A'. Can you explain this answer?
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