Why it is called 70S Ribosome , while it is made up of 30S and 50S sub...
All prokaryotes have 70S (where S=Svedberg units) ribosomes while eukaryotes contain larger 80S ribosomes in their cytosol. The 70S ribosome is made up of a 50S and 30S subunits. The 50S subunit contains the 23S and 5S rRNA while the 30S subunit contains the 16S rRNA.
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Why it is called 70S Ribosome , while it is made up of 30S and 50S sub...
70S Ribosome Structure
The term "70S ribosome" refers to the size of the ribosome complex found in prokaryotic cells, including bacteria and archaea. It is composed of two subunits: the small subunit (30S) and the large subunit (50S). Despite the individual sizes of the subunits, the combined size of the 30S and 50S subunits is approximately 70S.
30S Subunit
The 30S subunit is responsible for decoding the genetic information carried by messenger RNA (mRNA). It contains a single molecule of 16S ribosomal RNA (rRNA) and several proteins. The 16S rRNA plays a crucial role in recognizing the start codon on the mRNA and aligning it with the appropriate transfer RNA (tRNA) carrying the corresponding amino acid.
50S Subunit
The 50S subunit is involved in the catalysis of peptide bond formation during protein synthesis. It consists of two rRNA molecules (23S and 5S), along with numerous proteins. The 23S rRNA acts as a ribozyme, providing the catalytic activity required for peptide bond formation.
Joining of Subunits
The 30S and 50S subunits come together to form the functional 70S ribosome during the initiation of protein synthesis. This association occurs with the help of initiation factors and requires the recognition of specific sequences on the mRNA and the assembly of the initiation complex.
Importance of Subunit Separation
The ability of the ribosome to dissociate into its subunits is crucial for various cellular processes. It allows for the recycling of ribosomes after the completion of protein synthesis and enables the regulation of translation by controlling the availability of ribosomes for protein production.
Conclusion
In summary, the term "70S ribosome" refers to the size of the ribosome complex found in prokaryotic cells. It is composed of a small 30S subunit and a large 50S subunit. The individual sizes of these subunits are responsible for the name, even though they combine to form the 70S ribosome complex. The 30S subunit decodes the mRNA, while the 50S subunit catalyzes peptide bond formation. The ability of the ribosome to dissociate into its subunits is essential for various cellular processes.
Why it is called 70S Ribosome , while it is made up of 30S and 50S sub...
Due to overlapping of smaller unit by larger unit
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