Castel's intrinsic factor is connected with internal absorption ofa) Pyridoxine b) Riboflavin c) Thiamine d) Cobalamine Correct answer is option 'D'. Can you explain this answer?

Question

Castel's intrinsic factor is connected with internal absorption ofa)                                  Pyridoxine                               b)                                  Riboflavin                               c)                                  Thiamine                               d)                                  Cobalamine                               Correct answer is option 'D'. Can you explain this answer?

Answer

Castle's intrinsic factor is a relatively small mucoprotein secreted by the parietal cells of gastric glands and required for adequate absorption of vitamin B12 (cobalamin) for production of red blood cells

Answer

Castles intrinsic factor is essential for absorption of vitamin B12(cyanocobalamine is modification of vitamin B12)

Answer

Explanation:
Intrinsic factor is a glycoprotein secreted by the parietal cells of the stomach. It plays a crucial role in the absorption of vitamin B12 (cobalamin) in the small intestine.

Role of Intrinsic Factor:
The intrinsic factor binds to vitamin B12 in the stomach, protecting it from degradation by stomach acid. It forms a complex with vitamin B12, which is then transported to the ileum (the last part of the small intestine) where it is absorbed.

Connection with Cobalamin:
Vitamin B12, also known as cobalamin, is a water-soluble vitamin that is essential for various bodily functions, including the formation of red blood cells, DNA synthesis, and neurological function.

The absorption of vitamin B12 requires the presence of intrinsic factor. Without intrinsic factor, vitamin B12 cannot be effectively absorbed by the body. This is known as pernicious anemia, a condition characterized by vitamin B12 deficiency due to the lack of intrinsic factor.

Other Options:
a) Pyridoxine (Vitamin B6): The absorption of vitamin B6 does not depend on intrinsic factor. It is absorbed in the jejunum (part of the small intestine) through passive diffusion.

b) Riboflavin (Vitamin B2): The absorption of vitamin B2 does not require intrinsic factor. It is absorbed in the jejunum through a carrier-mediated process.

c) Thiamine (Vitamin B1): The absorption of vitamin B1 also does not depend on intrinsic factor. It is absorbed throughout the small intestine through passive diffusion.

Conclusion:
Intrinsic factor is specifically connected with the internal absorption of cobalamin (vitamin B12). It is essential for the effective absorption of vitamin B12 in the small intestine. Deficiency of intrinsic factor can lead to pernicious anemia and vitamin B12 deficiency.

Answer

It is connected with Vitamin B12 also called as cobalamine..

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