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During translation initiation in prokaryotes, a GTP molecule is needed in
[2003]
- a)association of 50 S subunit of ribosome with initiation complex
- b)formation of formyl-met-tRNA
- c)binding of 30 S subunit of ribosome with mRNA
- d)association of 30 S-mRNA with formylmet-tRNA
Correct answer is option 'D'. Can you explain this answer?
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During translation initiation in prokaryotes, a GTP molecule is needed...
For the formation of initiation complex during translation of mRNA, GTP is also required. The initiator AUG codes for the formylmethionine in prokaryotes.
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During translation initiation in prokaryotes, a GTP molecule is needed...
Translation initiation in prokaryotes
Translation initiation is the process by which protein synthesis begins in a cell. In prokaryotes, it involves the binding of the ribosome to the mRNA molecule and the recruitment of the initiator tRNA (formyl-methionine tRNA) to the ribosome. Several factors are involved in this process, including GTP (Guanosine triphosphate).
Role of GTP in translation initiation
GTP plays a crucial role in various steps of translation initiation in prokaryotes. Let's explore the options given in the question to understand why option 'D' is the correct answer.
a) Association of 50 S subunit of ribosome with initiation complex
During translation initiation, the small ribosomal subunit (30S) first associates with the mRNA molecule, forming the initiation complex. This step does not require GTP.
b) Formation of formyl-met-tRNA
Formyl-methionine tRNA (fMet-tRNA) is the initiator tRNA that carries the first amino acid, formyl-methionine, to the ribosome. The formation of fMet-tRNA is catalyzed by the enzyme aminoacyl-tRNA synthetase, which does not require GTP.
c) Binding of 30 S subunit of ribosome with mRNA
As mentioned earlier, the binding of the small ribosomal subunit (30S) with mRNA forms the initiation complex. This step does not require GTP.
d) Association of 30 S-mRNA with formylmet-tRNA
The correct answer is option 'D'. GTP is required for the association of the 30S-mRNA complex with the initiator tRNA (fMet-tRNA). This step is facilitated by initiation factors, particularly IF2 (initiation factor 2), which hydrolyzes GTP to GDP (Guanosine diphosphate) during the process. GTP hydrolysis provides energy for the proper positioning of the initiator tRNA on the ribosome.
Therefore, during translation initiation in prokaryotes, a GTP molecule is needed for the association of the 30S-mRNA complex with the formyl-methionine tRNA (fMet-tRNA). This step ensures the correct initiation of protein synthesis and the proper assembly of the ribosome.
Translation initiation is the process by which protein synthesis begins in a cell. In prokaryotes, it involves the binding of the ribosome to the mRNA molecule and the recruitment of the initiator tRNA (formyl-methionine tRNA) to the ribosome. Several factors are involved in this process, including GTP (Guanosine triphosphate).
Role of GTP in translation initiation
GTP plays a crucial role in various steps of translation initiation in prokaryotes. Let's explore the options given in the question to understand why option 'D' is the correct answer.
a) Association of 50 S subunit of ribosome with initiation complex
During translation initiation, the small ribosomal subunit (30S) first associates with the mRNA molecule, forming the initiation complex. This step does not require GTP.
b) Formation of formyl-met-tRNA
Formyl-methionine tRNA (fMet-tRNA) is the initiator tRNA that carries the first amino acid, formyl-methionine, to the ribosome. The formation of fMet-tRNA is catalyzed by the enzyme aminoacyl-tRNA synthetase, which does not require GTP.
c) Binding of 30 S subunit of ribosome with mRNA
As mentioned earlier, the binding of the small ribosomal subunit (30S) with mRNA forms the initiation complex. This step does not require GTP.
d) Association of 30 S-mRNA with formylmet-tRNA
The correct answer is option 'D'. GTP is required for the association of the 30S-mRNA complex with the initiator tRNA (fMet-tRNA). This step is facilitated by initiation factors, particularly IF2 (initiation factor 2), which hydrolyzes GTP to GDP (Guanosine diphosphate) during the process. GTP hydrolysis provides energy for the proper positioning of the initiator tRNA on the ribosome.
Therefore, during translation initiation in prokaryotes, a GTP molecule is needed for the association of the 30S-mRNA complex with the formyl-methionine tRNA (fMet-tRNA). This step ensures the correct initiation of protein synthesis and the proper assembly of the ribosome.
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During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer?
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During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer?.
During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for During translation initiation in prokaryotes, a GTP molecule is needed in[2003]a)association of 50 S subunit of ribosome with initiation complexb)formation of formyl-met-tRNAc)binding of 30 S subunit of ribosome with mRNAd)association of 30 S-mRNA with formylmet-tRNACorrect answer is option 'D'. Can you explain this answer?.
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