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During translation initiation in prokaryotes, GTP is required for
- a)Formation of formyl–met–tRNA
- b)Binding of 30 S submit of ribosome with mRNA
- c)Association of 30S–mRNA with formyl–met–tRNA
- d)Association of 50S submit of ribosome with initiation complex
Correct answer is option 'C'. Can you explain this answer?
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During translation initiation in prokaryotes, GTP is required fora)For...
During translation initiation in prokaryotes, GTP is required for the association of the 30S ribosomal subunit with the mRNA and formyl-methionine-tRNA (fMet-tRNA) to form the 30S-mRNA-fMet-tRNA initiation complex.
1. Translation Initiation in Prokaryotes:
Translation is the process by which the genetic information in mRNA is decoded to synthesize proteins. In prokaryotes, translation initiation involves the assembly of ribosomes on the mRNA to initiate protein synthesis.
2. Formation of the Initiation Complex:
Translation initiation begins with the binding of the small 30S ribosomal subunit to the mRNA. This binding is facilitated by initiation factors that recognize the Shine-Dalgarno sequence on the mRNA and the 16S rRNA of the 30S subunit. The Shine-Dalgarno sequence is a purine-rich region upstream of the start codon on the mRNA and is complementary to a sequence on the 16S rRNA.
3. GTP Requirement:
GTP (guanosine triphosphate) is a nucleotide that provides energy for various cellular processes. During translation initiation, GTP is required for the proper association of the 30S ribosomal subunit with the mRNA and the formyl-methionine-tRNA (fMet-tRNA).
4. Association of 30S-mRNA with fMet-tRNA:
Once the 30S subunit is bound to the mRNA, the next step is the association of the fMet-tRNA with the start codon on the mRNA. The fMet-tRNA is a specific tRNA molecule that carries the amino acid methionine with a formyl group attached (formyl-methionine). This aminoacyl-tRNA is specific to the initiation codon (usually AUG) and ensures the correct positioning of the ribosome for protein synthesis.
5. GTP Hydrolysis and Initiation Complex Formation:
GTP hydrolysis is required for the stable association of the 30S ribosomal subunit with the fMet-tRNA and mRNA. The hydrolysis of GTP to GDP provides the energy necessary for the formation of the 30S-mRNA-fMet-tRNA initiation complex. Once the initiation complex is formed, the large 50S ribosomal subunit associates with it to form the complete ribosome ready for protein synthesis.
Therefore, during translation initiation in prokaryotes, GTP is required for the association of the 30S ribosomal subunit with the mRNA and formyl-methionine-tRNA, leading to the formation of the initiation complex.
1. Translation Initiation in Prokaryotes:
Translation is the process by which the genetic information in mRNA is decoded to synthesize proteins. In prokaryotes, translation initiation involves the assembly of ribosomes on the mRNA to initiate protein synthesis.
2. Formation of the Initiation Complex:
Translation initiation begins with the binding of the small 30S ribosomal subunit to the mRNA. This binding is facilitated by initiation factors that recognize the Shine-Dalgarno sequence on the mRNA and the 16S rRNA of the 30S subunit. The Shine-Dalgarno sequence is a purine-rich region upstream of the start codon on the mRNA and is complementary to a sequence on the 16S rRNA.
3. GTP Requirement:
GTP (guanosine triphosphate) is a nucleotide that provides energy for various cellular processes. During translation initiation, GTP is required for the proper association of the 30S ribosomal subunit with the mRNA and the formyl-methionine-tRNA (fMet-tRNA).
4. Association of 30S-mRNA with fMet-tRNA:
Once the 30S subunit is bound to the mRNA, the next step is the association of the fMet-tRNA with the start codon on the mRNA. The fMet-tRNA is a specific tRNA molecule that carries the amino acid methionine with a formyl group attached (formyl-methionine). This aminoacyl-tRNA is specific to the initiation codon (usually AUG) and ensures the correct positioning of the ribosome for protein synthesis.
5. GTP Hydrolysis and Initiation Complex Formation:
GTP hydrolysis is required for the stable association of the 30S ribosomal subunit with the fMet-tRNA and mRNA. The hydrolysis of GTP to GDP provides the energy necessary for the formation of the 30S-mRNA-fMet-tRNA initiation complex. Once the initiation complex is formed, the large 50S ribosomal subunit associates with it to form the complete ribosome ready for protein synthesis.
Therefore, during translation initiation in prokaryotes, GTP is required for the association of the 30S ribosomal subunit with the mRNA and formyl-methionine-tRNA, leading to the formation of the initiation complex.
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During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer?
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During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer?.
During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for During translation initiation in prokaryotes, GTP is required fora)Formation of formyl–met–tRNAb)Binding of 30 S submit of ribosome with mRNAc)Association of 30S–mRNA with formyl–met–tRNAd)Association of 50S submit of ribosome with initiation complexCorrect answer is option 'C'. Can you explain this answer?.
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