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Fluid mosaic model was proposed by Singer and Nicolson. According to this model, there is a central lipid bilayer of phospholipids with their polar head group towards the outside and the non-polar tails pointing inwards. Some proteins are embedded in the lipid layer are called integral or intrinsic proteins and they cannot be separated from the membrane. There are large globular integral proteins which project beyond the lipid layer on both the sides. Superficially attached proteins are called extrinsic or peripheral proteins and can be easily removed. Some membrane lipids and integral proteins remains bound to oligosaccharides which project into the extracellular fluid.
Q. The interaction responsible for stabilizing plasma membrane is majorly:
  • a)
    covalent bonds
  • b)
    ionic bonds
  • c)
    hydrophobic interactions
  • d)
    hydrophilic interactions
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Fluid mosaic model was proposed by Singer and Nicolson. According to ...
Hydrophobic forces resulting from the effects on water force the lipids into a bilayer. Then hydrogen bonds, electrostatic attractions and van der Waals contacts further stabilize the membrane.
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Fluid mosaic model was proposed by Singer and Nicolson. According to ...
Interaction responsible for stabilizing plasma membrane:

The major interaction responsible for stabilizing the plasma membrane is hydrophobic interactions. These interactions play a crucial role in maintaining the integrity and fluidity of the lipid bilayer.

Fluid Mosaic Model and the Lipid Bilayer:

The fluid mosaic model of the plasma membrane proposes that the membrane is composed of a lipid bilayer with embedded proteins. The lipid bilayer consists of phospholipids, with their polar head groups facing the outside and the non-polar tails pointing inward. This arrangement creates a hydrophobic interior, which is impermeable to most substances.

Integral and Peripheral Proteins:

Integral proteins are embedded within the lipid bilayer and cannot be easily separated from the membrane. These proteins have hydrophobic regions that interact with the hydrophobic interior of the lipid bilayer. They play various roles in cell signaling, transport of molecules, and maintaining the structural integrity of the membrane.

On the other hand, peripheral proteins are superficially attached to the membrane and can be easily removed. These proteins interact with the surface of the membrane, primarily through electrostatic interactions and hydrogen bonding.

Role of Hydrophobic Interactions:

Hydrophobic interactions are the major force responsible for stabilizing the plasma membrane. The hydrophobic tails of phospholipids in the lipid bilayer interact with each other, creating a stable barrier that separates the intracellular and extracellular environments.

These hydrophobic interactions also play a crucial role in the organization and movement of integral proteins within the membrane. The hydrophobic regions of integral proteins interact with the hydrophobic interior of the lipid bilayer, anchoring them in place and providing stability to the membrane structure.

Other Interactions:

While hydrophobic interactions are the primary force involved in membrane stabilization, other interactions also contribute to the overall stability of the plasma membrane. These include:
- Covalent bonds: Some integral proteins may have covalent bonds with lipids or other proteins, providing additional stability to the membrane structure.
- Ionic bonds: Electrostatic interactions between charged amino acid residues in proteins and the polar head groups of phospholipids can also contribute to membrane stability.
- Hydrophilic interactions: Hydrophilic interactions between the polar head groups of phospholipids and water molecules in the surrounding environment help maintain the fluidity of the membrane.

However, hydrophobic interactions are the dominant force in stabilizing the plasma membrane due to the hydrophobic nature of the lipid bilayer. They ensure the proper organization and functioning of integral proteins and contribute to the overall stability and integrity of the membrane.
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Fluid mosaic model was proposed by Singer and Nicolson. According to this model, there is a central lipid bilayer of phospholipids with their polar head group towards the outside and the non-polar tails pointing inwards. Some proteins are embedded in the lipid layer are called integral or intrinsic proteins and they cannot be separated from the membrane. There are large globular integral proteins which project beyond the lipid layer on both the sides. Superficially attached proteins are called extrinsic or peripheral proteins and can be easily removed. Some membrane lipids and integral proteins remains bound to oligosaccharides which project into the extracellular fluid.Q. The interaction responsible for stabilizing plasma membrane is majorly:a)covalent bondsb)ionic bondsc)hydrophobic interactionsd)hydrophilic interactionsCorrect answer is option 'C'. Can you explain this answer?
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Fluid mosaic model was proposed by Singer and Nicolson. According to this model, there is a central lipid bilayer of phospholipids with their polar head group towards the outside and the non-polar tails pointing inwards. Some proteins are embedded in the lipid layer are called integral or intrinsic proteins and they cannot be separated from the membrane. There are large globular integral proteins which project beyond the lipid layer on both the sides. Superficially attached proteins are called extrinsic or peripheral proteins and can be easily removed. Some membrane lipids and integral proteins remains bound to oligosaccharides which project into the extracellular fluid.Q. The interaction responsible for stabilizing plasma membrane is majorly:a)covalent bondsb)ionic bondsc)hydrophobic interactionsd)hydrophilic interactionsCorrect answer is option 'C'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Fluid mosaic model was proposed by Singer and Nicolson. According to this model, there is a central lipid bilayer of phospholipids with their polar head group towards the outside and the non-polar tails pointing inwards. Some proteins are embedded in the lipid layer are called integral or intrinsic proteins and they cannot be separated from the membrane. There are large globular integral proteins which project beyond the lipid layer on both the sides. Superficially attached proteins are called extrinsic or peripheral proteins and can be easily removed. Some membrane lipids and integral proteins remains bound to oligosaccharides which project into the extracellular fluid.Q. The interaction responsible for stabilizing plasma membrane is majorly:a)covalent bondsb)ionic bondsc)hydrophobic interactionsd)hydrophilic interactionsCorrect answer is option 'C'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Fluid mosaic model was proposed by Singer and Nicolson. According to this model, there is a central lipid bilayer of phospholipids with their polar head group towards the outside and the non-polar tails pointing inwards. Some proteins are embedded in the lipid layer are called integral or intrinsic proteins and they cannot be separated from the membrane. There are large globular integral proteins which project beyond the lipid layer on both the sides. Superficially attached proteins are called extrinsic or peripheral proteins and can be easily removed. Some membrane lipids and integral proteins remains bound to oligosaccharides which project into the extracellular fluid.Q. The interaction responsible for stabilizing plasma membrane is majorly:a)covalent bondsb)ionic bondsc)hydrophobic interactionsd)hydrophilic interactionsCorrect answer is option 'C'. Can you explain this answer?.
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