Identify the microorganism which is responsible for the production of...
Microorganism responsible for cyclosporin A production
Trichoderma polysporum is the microorganism responsible for the production of the immunosuppressive molecule cyclosporin A.
Explanation
Cyclosporin A is a potent immunosuppressive agent that is widely used in the field of organ transplantation to prevent rejection of the transplanted organ. It works by inhibiting the activation and proliferation of T-lymphocytes, which are key players in the immune response. Cyclosporin A is produced by the fungus Trichoderma polysporum, which is commonly found in soil and decaying plant material.
Trichoderma polysporum is a filamentous fungus that belongs to the class Ascomycetes. It is capable of producing a wide range of secondary metabolites, including cyclosporin A. The biosynthesis of cyclosporin A in Trichoderma polysporum involves a complex pathway that requires the activity of several enzymes. The genes encoding these enzymes are clustered together in the genome of the fungus, and their expression is tightly regulated.
In conclusion, Trichoderma polysporum is the microorganism responsible for the production of cyclosporin A, a potent immunosuppressive agent used in organ transplantation.
Identify the microorganism which is responsible for the production of...
Bioactive molecule, cyclosporin A, that is used as an immunosuppressive agent in organ transplantpatients, is produced by the fungus, Trichoderma polysporum.
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