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Which  of the following substances, if introduced into the blood stream, would cause coagulation of blood at the site of its introduction ?
  • a)
    prothrombin
  • b)
    fibrinogen
  • c)
    thromboplastin
  • d)
    heparin
Correct answer is option 'C'. Can you explain this answer?
Verified Answer
Which of the following substances, if introduced into the blood stream...
Correct Answer: C
Solution 
               Lipoproteinaceous, thromboplastin is released by the injured tissue. This reacts with \[C{{a}^{++}}\] ions present in blood and forms a proteinaceous enzyme called prothrombinase. Later in the presence of \[C{{a}^{++}}\] inactivates heparin (anticoagulant) and catalyses prothrombin (inactive plasma protein) into an active thrombin protein. Thrombin acts as an enzyme and catalyses fibrinogen (a soluble plasma protein) into an insoluble fibre like polymer, fibrin. These fibres form a dense network upon the wound and trap blood corpuscles (WBCs, RBCs and platelets) and thus form a clot. This clot seals the wound and stop bleeding. In blood vessels, thromboplastin do not release due to which blood does not clot. But external thromboplastin to blood will cause blood clotting at the site of its introduction due to formation of prothrombinase.
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Most Upvoted Answer
Which of the following substances, if introduced into the blood stream...
Because thromboplastin will convert pro thromin into thrombin and thrombin will convert fibrinolysin to fibrin and this fibrin would be use for blood coagulation.all other options are inactive form and they are converted into active form by thromboplastin
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Which of the following substances, if introduced into the blood stream...


Thromboplastin

Thromboplastin is a substance that plays a crucial role in the process of blood clotting. When introduced into the bloodstream, thromboplastin initiates the extrinsic pathway of coagulation, leading to the formation of a blood clot at the site of its introduction.

Process of Blood Coagulation

- Thromboplastin converts prothrombin into thrombin, which then converts fibrinogen into fibrin.
- Fibrin forms a mesh-like structure that traps platelets and other blood cells, forming a blood clot.
- This clotting process helps to prevent excessive bleeding and promotes wound healing.

Role of Thromboplastin

- Thromboplastin is essential for the initiation of the coagulation cascade and the formation of a stable blood clot.
- Without thromboplastin, the blood would not be able to clot effectively, leading to increased risk of bleeding and hemorrhage.

In conclusion, the introduction of thromboplastin into the bloodstream would cause coagulation of blood at the site of its introduction by triggering the clotting cascade.
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Which of the following substances, if introduced into the blood stream, would cause coagulation of blood at the site of its introduction ?a)prothrombinb)fibrinogenc)thromboplastind)heparinCorrect answer is option 'C'. Can you explain this answer?
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