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Haemophilic female marries normal male, the theoretical ratio of their offsprings regarding hemophilia will be
- a)all offsprings are haemophilic
- b)all girls are haemophilic
- c)all sons are haemophilic
- d)half daughters and half sons are haemophilic
Correct answer is option 'C'. Can you explain this answer?
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Haemophilic female marries normal male, the theoretical ratio of thei...
The correct answer is option 'C': all sons are haemophilic.
Explanation:
When a haemophilic female marries a normal male, there are certain genetic factors that need to be considered in order to determine the likelihood of their offspring inheriting hemophilia.
1. Hemophilia is a sex-linked recessive disorder that is carried on the X chromosome. Females have two X chromosomes (XX), while males have one X and one Y chromosome (XY).
2. If a female is haemophilic, it means that both of her X chromosomes carry the hemophilia gene. Since the male only has one X chromosome, he is not a carrier of the hemophilia gene.
3. When the female haemophilic marries a normal male, there are two possible genotypes for the female: XhXh (haemophilic) or XhX (carrier). The male genotype is XY.
4. The possible genotypes for their offspring are as follows:
- Female offspring: XhXh (haemophilic) or XhX (carrier)
- Male offspring: XY (normal)
5. Since the male offspring only receives the Y chromosome from the father, they will not inherit the hemophilia gene. Therefore, all sons of a haemophilic female and normal male will be haemophilia-free.
6. However, all daughters of a haemophilic female and normal male have a 50% chance of being haemophilic (XhXh) and a 50% chance of being carriers (XhX). This is because the daughters receive one X chromosome from the mother (which carries the hemophilia gene) and one X chromosome from the father (which is normal).
In conclusion, when a haemophilic female marries a normal male, all of their sons will be normal (not haemophilic), while their daughters will have a 50% chance of being haemophilic and a 50% chance of being carriers.
Explanation:
When a haemophilic female marries a normal male, there are certain genetic factors that need to be considered in order to determine the likelihood of their offspring inheriting hemophilia.
1. Hemophilia is a sex-linked recessive disorder that is carried on the X chromosome. Females have two X chromosomes (XX), while males have one X and one Y chromosome (XY).
2. If a female is haemophilic, it means that both of her X chromosomes carry the hemophilia gene. Since the male only has one X chromosome, he is not a carrier of the hemophilia gene.
3. When the female haemophilic marries a normal male, there are two possible genotypes for the female: XhXh (haemophilic) or XhX (carrier). The male genotype is XY.
4. The possible genotypes for their offspring are as follows:
- Female offspring: XhXh (haemophilic) or XhX (carrier)
- Male offspring: XY (normal)
5. Since the male offspring only receives the Y chromosome from the father, they will not inherit the hemophilia gene. Therefore, all sons of a haemophilic female and normal male will be haemophilia-free.
6. However, all daughters of a haemophilic female and normal male have a 50% chance of being haemophilic (XhXh) and a 50% chance of being carriers (XhX). This is because the daughters receive one X chromosome from the mother (which carries the hemophilia gene) and one X chromosome from the father (which is normal).
In conclusion, when a haemophilic female marries a normal male, all of their sons will be normal (not haemophilic), while their daughters will have a 50% chance of being haemophilic and a 50% chance of being carriers.
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