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Suppose you are developing a new drug, and have found that when it is administered in humans there is a substantial increase in the volume of urine produced. When you administer antidiuretic hormone (ADH, or vasopressin) at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:
  • a)
    Blocks the receptors for ADH on the collecting ducts of the kidney.
  • b)
    Blocks the release of ADH from the pituitary.
  • c)
    Mimics the action of ADH.
  • d)
    Decreases blood pressure.
Correct answer is option 'B'. Can you explain this answer?
Most Upvoted Answer
Suppose you are developing a new drug, and have found that when it is ...
The new drug we would have developed would block the adh release therby preventing adh action of reabsorption of water from urine making it more dilute. that's y op B.
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Suppose you are developing a new drug, and have found that when it is ...
Explanation:


The observation states that when the new drug is administered in humans, there is a substantial increase in the volume of urine produced. However, when antidiuretic hormone (ADH) is administered at the same time, the volume of urine returns to normal. Based on these observations, the best hypothesis that fits these observations is option 'B': the new drug blocks the release of ADH from the pituitary. Here's an explanation of why this hypothesis is the most appropriate:

1. ADH and urine production:
ADH, also known as vasopressin, is a hormone produced by the pituitary gland. One of its main functions is to regulate the volume of urine produced by the kidneys. ADH acts on the collecting ducts of the kidneys to increase their permeability to water, allowing more water to be reabsorbed back into the bloodstream. This leads to a decrease in urine volume.

2. Effect of the new drug:
The observation states that when the new drug is administered, there is a substantial increase in the volume of urine produced. This suggests that the drug is interfering with the normal regulation of urine production, likely by affecting the action of ADH.

3. Effect of administering ADH:
When ADH is administered at the same time as the new drug, the volume of urine returns to normal. This indicates that the drug's effect on urine production can be reversed by providing additional ADH.

4. Conclusion:
Based on these observations, it can be concluded that the new drug is blocking the release of ADH from the pituitary gland. This would explain why the volume of urine increases when the drug is administered and why the administration of ADH reverses this effect. By blocking ADH release, the drug is disrupting the normal regulation of urine production, leading to an increase in urine volume.
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Suppose you are developing a new drug, and have found that when it is administered in humans there is a substantial increase in the volume of urine produced. When you administer antidiuretic hormone (ADH, or vasopressin) at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:a)Blocks the receptors for ADH on the collecting ducts of the kidney.b)Blocks the release of ADH from the pituitary.c)Mimics the action of ADH.d)Decreases blood pressure.Correct answer is option 'B'. Can you explain this answer?
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Suppose you are developing a new drug, and have found that when it is administered in humans there is a substantial increase in the volume of urine produced. When you administer antidiuretic hormone (ADH, or vasopressin) at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:a)Blocks the receptors for ADH on the collecting ducts of the kidney.b)Blocks the release of ADH from the pituitary.c)Mimics the action of ADH.d)Decreases blood pressure.Correct answer is option 'B'. Can you explain this answer? for NEET 2024 is part of NEET preparation. The Question and answers have been prepared according to the NEET exam syllabus. Information about Suppose you are developing a new drug, and have found that when it is administered in humans there is a substantial increase in the volume of urine produced. When you administer antidiuretic hormone (ADH, or vasopressin) at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:a)Blocks the receptors for ADH on the collecting ducts of the kidney.b)Blocks the release of ADH from the pituitary.c)Mimics the action of ADH.d)Decreases blood pressure.Correct answer is option 'B'. Can you explain this answer? covers all topics & solutions for NEET 2024 Exam. Find important definitions, questions, meanings, examples, exercises and tests below for Suppose you are developing a new drug, and have found that when it is administered in humans there is a substantial increase in the volume of urine produced. When you administer antidiuretic hormone (ADH, or vasopressin) at the same time, the volume of urine returns to normal. Which hypothesis best fits these observations? The new drug:a)Blocks the receptors for ADH on the collecting ducts of the kidney.b)Blocks the release of ADH from the pituitary.c)Mimics the action of ADH.d)Decreases blood pressure.Correct answer is option 'B'. Can you explain this answer?.
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